The orange-fluorescent RhodZin™-3 zinc indicator exhibits a dramatic 75-fold increase in fluorescence at saturating levels of Zn²⁺. The cell-permeant AM ester form of RhodZin-3 (R36351) effectively localizes into mitochondria and is a valuable tool for investigating the physiological consequences of mitochondrial Zn²⁺ sequestration. The cell-impermeant RhodZin™-3 salt (R36350) can be used to measure extracellular Zn²⁺ concentrations.

Fluorescent Zinc Indicators Specifications:
• Label (Ex/Em): RhodZin™-3 (~550/575 nm)
• K_d (Zn²⁺) (in buffer): ~65 nM
• Lyophilized product may be dissolved in distilled water or aqueous buffer for use
• Product is typically loaded into cells using microinjection or diffusion from patch pipette

Find Fluorescent Indicators for Zinc and Other Metal Ions
We offer a number of fluorescent indicators to determine polyvalent cation concentrations inside cells, to follow metal ion transport through ion channels, to make measurements in environmental samples, and more. Review Fluorescent Indicators for Zn²⁺ and Other Metal Ions—Section 19.7 in the Molecular Probes® Handbook for more information on these products.

For Research Use Only. Not for human or animal therapeutic or diagnostic use.