The CD8, clone 3B5, Qdot® 800 nanocrystal conjugate is a mouse monoclonal antibody (mAb) that recognizes the human CD8 antigen also known as T8 and Lyt2,3. The Qdot® 800 nanocrystal conjugate may be used in the same way as conventional antibody conjugates and is most often used with 405 nm excitation, permitting simultaneous multicolor labeling of multiple targets off the violet laser. Alternatively, the nanocrystal can be excited by any laser up to the wavelength at which it absorbs.

Antibody Specifications

Description:

CD8, Mouse IgG2a monoclonal

Label:

Qdot® 800 nanocrystal

Validated Application:

Flow Cytometry

Species Reactivity:

Human

Ex/Em and laser configuration:

405 (488 or 647)/800 nm, violet , blue or red laser

Clone ID:

3B5

Leukocyte Workshop Status:

Leukocyte Typing V

Regulatory Status:

RUO

Specificity for CD8
This antibody recognizes the CD8 antigen, also known as T8 and Lyt2,3. The antibody specifically recognizes the α-chain alone, as well as the αβ heterodimer. During T-cell activation, CD8 is a co-receptor for the T-cell receptor (TCR) by binding MHC Class I molecules. CD8 is expressed on cytotoxic T-cells and subsetsof thymocytes.

For Research Use Only
Not for use in diagnostic procedures.

Related Links
Use the primary antibody selector tool to see the full list of CD8 antibodies.
You can get additional information about Qdot® nanocrystals in flow cytometry and use the Spectraviewer to help you plan your experiments. Additional general information about Life Technologies flow cytometry products and support is also available.