The CD45, clone HI30, Qdot® 655 nanocrystal conjugate is a mouse monoclonal antibody (mAb) that is reactive to the human CD45 antigen and recognizes the expressed product of the PTPRC gene. The Qdot® 655 nanocrystal conjugate may be used in the same way as conventional antibody conjugates and is most often used with 405 nm excitation, permitting simultaneous multicolor labeling of multiple targets off the violet laser. Alternatively, the nanocrystal can be excited by any laser up to the wavelength at which it absorbs.


Specificity for CD45
This antibody recognizes the CD45 antigen, also known as Leukocyte Common Antigen (LCA). CD45 is an essential regulator of leukocyte activation and development. CD45 is a protein tyrosine phosphatase that dephosphorylates Src family protein kinases. This activity is required for signal transduction that is induced by T and B cell antigen receptor engagement, cytokine signaling, and Fc receptor stimulation. CD45 is expressed on all cells of hematopoietic origin with the exception of platelets and red blood cells and their immediate precursors. CD45 is also a pan leukocyte marker.

For Research Use Only
Not for use in diagnostic procedures.

Related Links
Use the primary antibody selector tool to see the full list of CD45 antibodies.
You can get additional information about Qdot® nanocrystals in flow cytometry and use the Spectraviewer to help you plan your experiments. Additional general information about Life Technologies flow cytometry products and support is also available.