The CD3, clone S4.1, Qdot® 800 nanocrystal conjugate is a monoclonal antibody (mAb) that is reactive to the human CD3 antigen and recognizes the expressed product of the CD3D gene. The Qdot® 800 nanocrystal conjugate may be used in the same way as conventional antibody conjugates and is most often used with 405 nm excitation, permitting simultaneous multicolor labeling of multiple targets off the violet laser. Alternatively, the nanocrystal can be excited by any laser up to the wavelength at which it absorbs.

Antibody Specifications

Description:

CD3, Mouse IgG2a monoclonal

Label:

Qdot® 800 nanocrystal

Validated Application:

Flow Cytometry

Species Reactivity:

Human

Ex/Em and laser configuration:

405 (488 or 647)/800 nm, violet, blue or red laser

Clone ID:

S4.1 (also known as 7D6)

Leukocyte Workshop Status:

Leukocyte Typing V

Regulatory Status:

RUO

Specificity for CD3
This antibody recognizes the CD3 antigen is responsible for T-cell receptor expression and signaling. It is comprised of 5 individual proteins and, in mammals, is composed of two CD3ε chains, a CD3γ chain, a CD3δ chain, a CD3β chain, and a CD3α chain. This CD3 receptor complex is expressed on thymocytes, T-cells and some NK cells.

For Research Use Only
Not for use in diagnostic procedures.

Related Links
For the full list of all CD3 antibodies available, please visit the primary antibody search tool.
You can get additional information about Qdot® nanocrystals in flow cytometry and use the Spectraviewer to help you plan your experiments. Additional general information about Life Technologies flow cytometry products and support is also available.