Recombinant Human Thrombopoietin (TPO) is a bioactive protein intended for use in cell culture applications. TPO is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, which is the product of the myeloproliferative leukemia virus oncogene. Recombinant Human Thrombopoeitin (TPO) is one of the many GIBCO® recombinant bioactive proteins available from Life Technologies. This is the 10 microgram size.

  • High purity—minimal interference from other proteins or contaminants
  • High biological activity—more results with less protein
  • Proven compatibility—GIBCO® proteins bioassayed with GIBCO® media

High Purity Recombinant Bioactive Protein
Recombinant Human Thrombopoietin (TPO) is one of more than 250 GIBCO® recombinant proteins available from Life Technologies. To help ensure GIBCO® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to help ensure a biologically active protein.

High Biological Activity
In-house activity testing of Recombinant Human Thrombopoeitin (TPO) includes cell proliferation, cytotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, and protease assays. Recombinant Human Thrombopoietin (TPO) specific activity is determined by the dose-dependent stimulation of the proliferation of human TF-1 cells (human erythroleukemic indicator cell line).

Proven Compatibility
GIBCO® proteins are bioassayed with GIBCO® media. Since 1962, GIBCO® has been a consistent provider of high quality media, reagents, and sera for reliable cell culture.

We also offer a selection of growth factors for use in cell therapy applications through our GIBCO® Cell Therapy Systems (CTS™) product line.

For Research Use Only. Not intended for any animal or human therapeutic or diagnostic use.

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