Recombinant Human Bone Morphogenetic Protein 2 (BMP2)is a bioactive protein intended for use in cell culture applications. BMP2is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo
in an extraskeletal site. BMP2 acts as a disulfide-linked homodimer and induces bone and cartilage formation.
• High purity
—no interference from other proteins or contaminants
• High biological activity
—more results with less protein
• Proven compatibility
—Gibco® proteins bioassayed with Gibco® mediaHigh Purity Recombinant Bioactive Protein
Recombinant Human Bone Morphogenetic Protein 2 is one of more than 250 Gibco® recombinant proteins available from Life Technologies. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human Bone Morphogenetic Protein 2 (BMP2)specific activity is determined by the dose dependent induction of alkaline phosphatase in mouse chondrogenic cell line ATDC5.Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.See our selection of recombinant Gibco® growth factors
For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.