Recombinant Human TRAIL is a bioactive protein intended for use in cell culture applications. TRAIL preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3.
• High purity
—no interference from other proteins or contaminants
• High biological activity
—more results with less protein
• Proven compatibility
—Gibco® proteins bioassayed with Gibco® mediaHigh Purity Recombinant Bioactive Protein
Recombinant Human TRAIL is one of more than 250 Gibco® recombinant proteins available from Life Technologies. To help ensure Gibco® growth factors are of the highest quality, each protein is analyzed for purity along with structural homogeneity to ensure a biologically active protein.High Biological Activity
In-house activity testing of Gibco® Recombinant Proteins includes cell proliferation, cytotoxicity, chemotaxis, calcium flux, secondary cytokine up-regulation, induction of surface antigen expression, antiviral, and protease assays. Recombinant Human TRAIL specific activity is determined by dose-dependent induction of apoptosis with U343 mg cells.Proven Compatibility
Gibco® proteins are bioassayed with Gibco® media. Since 1962, Gibco® has been the consistent provider of high quality media, reagents, and sera for reliable cell culture.See our selection of recombinant Gibco® growth factors
For Research Use Only. Not intended for animal or human diagnostic or therapeutic use.