CDK Assay Kit, Rb^ING Green -"DISCONTINUED"

Cat. No. P2929

The retinoblastoma protein (Rb) is known as a tumor suppressor protein that acts via inhibition of cell cycle progression from the G₁ to the S phase. Rb's control over cell cycle progression is determined by its phosphorylation by cyclin dependent kinases (CDKs). One site on Rb that is phosphorylated and has an important impact on the regulation of cellular events is Threonine 252.