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Ready-to use system: Upon proliferation in StemPro® NSC-SFM, >80% of the cells retain their undifferentiated Phenotype, good post-thaw cell viability (≥ 50%), and supports differentiation into Oligodendrocytes and Astrocytes. Gibco® Rat Glial Precursor Cells (GPC) offer researchers ready access to high quality cells and eliminate the time and effort to isolate these highly sensitive cells in house. Glial Precursor Cells are isolated from the cortex of newborn Sprague-Dawley rats. The cells are isolated under sterile conditions, expanded in complete StemPro® NSC SFM, and cryopreserved at passage 2 (P2). Each vial contains 1 × 106 cells/ml viable cells (post-thaw) that can be expanded once to give >2 fold increase of cells. Upon proliferation in StemPro® NSC SFM, >80% of cells retain their undifferentiated Phenotype and can be differentiated into Oligodendrocytes and Astrocytes. Glial Precursor Cells are the restricted progenitors, and the majority of their down stream progeny are Oligodendrocytes and Astrocytes. Oligodendrocytes produce myelin to protect neurons and secure proper signal transduction. Demyelination is involved with critical diseases, such as multiple sclerosis, Addison-Schilder Disease (ALD) etc.
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