The FluoZin™-3 indicator is a Zn2+
-selective indicator with a structure that resembles fluo-4. FluoZin™-3 exhibits high Zn2+
-binding affinity that is unperturbed by Ca2+
concentrations up to at least 1 µM. In addition, FluoZin™-3 exhibits a >50-fold increase in fluorescence in response to saturating levels of Zn2+
. Although imaging applications of FluoZin™-3 are predominant, cell-based microplate assays and flow cytometry protocols have also been developed. FluoZin™-3 indicator is available in a cell-permeant and a cell-impermeant form.Fluorescent Zinc Indicators Specifications:
• Label (Ex/Em): FluoZin™-3 (~494/516 nm)
• Kd (Zn2+) (in buffer): ~15 nM
• Lyophilized product may be dissolved in distilled water or aqueous buffer for use
• Product is typically loaded into cellsusing microinjection or diffusion from patch pipetteFind Fluorescent Indicators for Zinc and Other Metal Ions
We offer a number of fluorescent indicators to determine polyvalent cation concentrations inside cells, to follow metal ion transport through ion channels, to make measurements in environmental samples, and more. Review Fluorescent Indicators for Zn2+ and Other Metal Ions—Section 19.7
in the Molecular Probes® Handbook for more information on these products.
For Research Use Only. Not for human or animal therapeutic or diagnostic use.