A synthetic miRNA mimic for miRNA functional analysis and target site validation. 5 nmol is supplied.

• Ambion® Pre-designed molecules for miRNAs listed in miRBase—custom design available
• Optimized design results in correct strand utilization by RISC
• Purified and ready to transfect

Ambion® Pre-miR™ miRNA Precursor Molecules are small, chemically modified, double-stranded RNA molecules designed to mimic endogenous mature miRNAs. This ready-to-use miRNA mimic can be introduced into cells using transfection or electroporation parameters similar to those used for siRNAs. They enable detailed study of miRNA biological effects via miRNA gain-of-function experiments, such as:
• Screening for miRNAs that regulate the expression of a gene
• miRNA target site identification and validation
• Screening for miRNAs that affect a cellular process