The proprietary patented magnetic separation technology with which the Pathatrix® Auto Instrument
performs pathogen enrichment and purification occurs within plastic disposable vessels loaded into a Pathatrix® Auto Cartridge. Each Pathatrix Auto Cartridge can be loaded and run independently of the others, and each Pathatrix Auto Instrument has slots for five cartridges.
Contaminated samples are first added to the consumable sample vessel. Paramagnetic beads, surface-modified for pathogen capture, are then added, and the sample vessel and attached elution vessel are loaded into the Pathatrix Auto Cartridge. The Pathatrix Auto Instrument uses magnets housed in the Pathatrix Auto Cartridge to capture the beads, and then efficiently recirculates the sample over the captured beads. Target organisms are retained by the immobilized beads, and after an automated washing and elution step, the isolated organisms are ready for downstream detection. The entire process is automated and takes only about 15 minutes.
Although the Pathatrix® Auto Instrument includes 5 Pathatrix® Auto Cartridges, these additional cartridges may be purchased, either as replacements, or to provide the convenience of being able to load samples while others are running in the instrument.
A Pathatrix® Auto Cartridge Rack
(ordered separately) serves as a stable platform for a set of 5 cartridges during loading and transport.