The Alexa Fluor 488 chicken anti—rat IgG is labeled with our exceptionally bright, photostable Alexa Fluor 488 dye (which is spectrally similar to fluorescein) and is prepared from affinity-purified antibodies that react with IgG heavy chains and all classes of immunoglobulin light chains from rat. Chicken antibodies lack a classic "Fc" domain and will not bind to mammalian IgG Fc receptors. To minimize crossreactivity, the antibody has been adsorbed against human and rabbit IgG prior to conjugation.