The CD79a, clone HM47, APC conjugate is a mouse monoclonal antibody (mAb) that recognizes the human CD79a antigen. APC (allophycocyanin) is one of the brightest dyes used today. It is a stable and highly soluble phycobiliprotein, which provides maximal absorbance and fluorescence without susceptibility to internal or external fluorescence quenching. APC provides almost perfect quantum efficiencies and molar extinction coefficients. Use of APC in antibody conjugates results in probes with greatly enhanced detectability.


Specific for CD79a
CD79a is a type I integral membrane protein that is a member of the immunoglobulin (Ig) superfamily. CD79a is expressed early in B cell development and found throughout B cells development into plasma cells. It is also weakly expressed in some precursors of T-cell and myeloid cells. CD79a forms a disulphide-associated heterodimer with CD79b (B29). The heterodimer of CD79a/CD79b interacts with membrane bound Ig to form the B cell antigen complex, which allows the cell to respond to antigens on its surface. The CD79a mouse anti-human monoclonal antibody (mAb) recognizes the cytoplasmic domain of the human CD79a antigen.

Research Use Only
For Research Use Only. Not intended for human or animal therapeutic or diagnostic use.

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