The CD278, clone C398.4A, PerCP-Cy®5.5 conjugate is an Armenian hamster monoclonal antibody (mAb) that recognizes the mouse, rat and human CD278 (ICOS) antigen. The PerCP-Cy®5.5 tandem conjugate combines the peridinin-chlorophyll proteins (PerCP) complexes, found in nature, with the Cy®5.5 cyanine dye; thereby permitting simultaneous multicolor labeling and detection of multiple targets by utilizing a single excitation source – the 488 nm line of an argon-ion laser.


Specific for CD278
CD278, also known as inducible costimulatory molecule (ICOS), is a co-stimulatory molecule that forms homodimers and is expressed on activated T-cells and a subset of thymocytes. It is involved in the stimulation of cell proliferation, Th2 cell development, and B cell germinal center formation within the humoral immune response. The CD278 (ICOS) hamster monoclonal antibody (mAb) reacts with the human, mouse, and rat CD278 antigens.

Research Use Only
For Research Use Only. Not intended for human or animal therapeutic or diagnostic use.

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