|CD137 (4-1BB), mouse IgG1 monoclonal|
Ex/Em and laser configuration:
|482/695 nm, blue laser|
Leukocyte Workshop Status:
|Leukocyte Typing VI C-7|
Specific for CD137
CD137 is a type I membrane protein belonging to the tumor necrosis factor (TNF) receptor superfamily. It is expressed on activated T-cells where it is involved in T-cell proliferation and survival, and on monocytes where it induces activation and proliferation. In addition, CD137 expression is found on follicular dendritic cells, NK cells, granulocytes, and cells of blood vessel walls at sites of inflammation. CD137 is known to enhance the immune system of mice enough to eliminate tumors.
Research Use Only
For Research Use Only. Not intended for human or animal therapeutic or diagnostic use.
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