|CD274 (B7-H1, PD-L1), rat IgG2b monoclonal|
Ex/Em and laser configuration:
|488/767 nm, blue laser|
Leukocyte Workshop Status:
Specific for CD274
CD274, also known as B7 homolog 1 (B7-H1) or programmed cell death 1 ligand 1 (PD-L1), belongs to the B7 family of the immunoglobulin (Ig) superfamily and is a type I transmembrane glycoprotein. It is expressed on B cells, T cells, NK cells, monocytes, dendritic cells, and IFN-γ activated endothelial cells. CD274 is involved in the co-stimulation of T-cell growth and cytokine production; however, upon interaction with its receptor, PD-1 (PDCD1), CD274 will inhibit T-cell proliferation and cytokine production.
Research Use Only
For Research Use Only. Not intended for human or animal therapeutic or diagnostic use.
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