|CD21/CD35, rat IgG2a monoclonal|
Ex/Em and laser configuration:
|482/695 nm, blue laser|
Leukocyte Workshop Status:
Specific for CD21/CD35
The CD21/CD35 rat monoclonal antibody (mAb) recognizes an epitope that is shared by both CD21, also known as complement receptor 2 (CR2) and CD35, also known as complement receptor 1 (CR1). The CD21 protein binds C3d and iC3b complement fragments and acts as a receptor of Epstein-Barr virus; while the CD35 protein binds C3b, iC3b, C4b, and iC4b complement fragments. The CD21/CD35 shared epitope is primarily expressed on B lymphocytes, mast cells, follicular dendritic cells, macrophages, and activated granulocytes. It is a component of the B-cell antigen receptor complex and is involved in signal transduction.
Research Use Only
For Research Use Only. Not intended for human or animal therapeutic or diagnostic use.
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