The CD14, clone Sa14-2, PerCP-Cy®5.5 conjugate is a rat monoclonal antibody (mAb) that recognizes the mouse CD14 antigen. The PerCP-Cy®5.5 tandem conjugate combines the peridinin-chlorophyll proteins (PerCP) complexes, found in nature, with the Cy®5.5 cyanine dye; thereby permitting simultaneous multicolor labeling and detection of multiple targets by utilizing a single excitation source – the 488 nm line of an argon-ion laser.


Specific for CD14
CD14 (cluster of differentiation 14) is part of the innate immune system is involved in the clearance of gram-negative pathogens. CD14 exists in two forms. It is either anchored to the cell membrane by a glycosylphosphatidylinositol tail (GPI-linked) and called mCD14 (48 kDa) or it is a soluble protein called sCD14 (56 kDa). The mCD14 isoform is expressed on macrophages, dendritic cells, Kupffer cells, hepatocytes, and granulocytes; while the sCD14 isoform appears after cells shed mCD14 or is directly secreted from intracellular vesicles.

Research Use Only
For Research Use Only. Not intended for human or animal therapeutic or diagnostic use.

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