|I-Ab, mouse IgG2a monoclonal|
Ex/Em and laser configuration:
|488/767 nm, blue laser|
Leukocyte Workshop Status:
Specific for I-Ab
The I-Ab mouse monoclonal antibody (mAb) reacts with the I-Ab haplotype of major histocompatibility complex (MHC) class II molecules, which are predominantly expressed on antigen presenting cells that include B lymphocytes, macrophages, dendritic cells, and certain epithelial cells. MHC Class II molecules are also expressed on a subset of T-cells from mice with the H-2b haplotype, as well as being involved in antigen presentation to T-cells expressing CD3/TCR and CD4 receptors. The I-Ab mouse mAb crossreacts with H-2k and H-2u haplotypes, but not other haplotypes (d, f, q, r, s).
For Research Use Only
Not intended for human or animal therapeutic or diagnostic use.
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