The I-A/I-E, clone M5/114.14.2, PerCP-Cy®5.5 conjugate is a rat monoclonal antibody (mAb) that recognizes the shared determinant on the I-Ab,d,q and I-Ed,k alloantigens. The PerCP-Cy®5.5 tandem conjugate combines the peridinin-chlorophyll proteins (PerCP) complexes, found in nature, with the Cy®5.5 cyanine dye; thereby permitting simultaneous multicolor labeling and detection of multiple targets by utilizing a single excitation source – the 488 nm line of an argon-ion laser.


Specific for I-A/I-E
The I-A/I-E rat monoclonal antibody (mAb) reacts with the mouse major histocompatibility complex (MHC) class II I-A/I-E molecules, which are expressed on antigen presenting cells (including B cells) and a subset of T-cells from mice carrying the H-2 b, H-2 d, H-2 q, and H-2 r haplotypes. These class II molecules are involved in antigen presentation to T-cells expressing CD3/TCR and CD4 receptors.

For Research Use Only
Not intended for human or animal therapeutic or diagnostic use.

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