The CD80, clone 16-10A1, PerCP-Cy®5.5 conjugate is an Armenian hamster monoclonal antibody (mAb) that recognizes the mouse CD80 antigen. The PerCP-Cy®5.5 tandem conjugate combines the peridinin-chlorophyll proteins (PerCP) complexes, found in nature, with the Cy®5.5 cyanine dye; thereby permitting simultaneous multicolor labeling and detection of multiple targets by utilizing a single excitation source – the 488 nm line of an argon-ion laser.


Specific for CD80
CD80 (cluster of differentiation 80) is a highly glycosylated member of the immunoglobulin (Ig) superfamily. CD80 is constitutively expressed on dendritic cells, monocytes, macrophages, and inducibly expressed on activated B and T cells. It is the ligand for two T-cell surface receptors. Specifically with the CD28 receptor, CD80 plays a co-stimulatory role in T-cell activation, proliferation, and cytokine production for autoregulation and intercellular association; and with the CD152 (CTLA-4) receptor, where CD80 plays an inhibitory role in T-cells for attenuation of regulation and cellular disassociation.

For Research Use Only
Not intended for human or animal therapeutic or diagnostic use.

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