|CD127 (IL-7Rα), Rat IgG2a monoclonal|
|PerCP-Cy®5.5 tandem dye|
Ex/Em and laser configuration:
|482/695 nm, blue laser|
Leukocyte Workshop Status:
The rat anti-mouse CD127 (IL-7Rα) monoclonal antibody (mAb) reacts with CD127, which is the α subunit of the mouse IL-7 receptor. CD127 is expressed by immature B cells in the bone marrow, by double-negative (CD4–/CD8n‐) and single-positive (CD4+ or CD8+) thymocytes; but not by double-positive (CD4+/CD8+) thymocytes. Mature T-cells in the periphery express CD127 at low level. The rat anti-mouse CD127 (IL-7Rα) mAb has inhibited binding of IL-7 to its receptor and has been utilized in in vivo and in vitro studies of IL-7 in T and B cell development and activation.
Research Use Only
Not intended for human or animal therapeutic or diagnostic use.
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