The CD127 (IL-7Rα), clone A7R34, PerCP-Cy^®5.5 conjugate is a rat monoclonal antibody (mAb) that recognizes mouse CD127. The PerCP-Cy^®5.5 tandem conjugate combines the peridinin-chlorophyll proteins (PerCP) complexes, found in nature, with the Cy^®5.5 cyanine dye; thereby permitting simultaneous multicolor labeling and detection of multiple targets by utilizing a single excitation source - the 488 nm line of an argon-ion laser.


CD127 (IL-7Rα)
The rat anti-mouse CD127 (IL-7Rα) monoclonal antibody (mAb) reacts with CD127, which is the α subunit of the mouse IL-7 receptor. CD127 is expressed by immature B cells in the bone marrow, by double-negative (CD4–/CD8n‐) and single-positive (CD4+ or CD8+) thymocytes; but not by double-positive (CD4+/CD8+) thymocytes. Mature T-cells in the periphery express CD127 at low level. The rat anti-mouse CD127 (IL-7Rα) mAb has inhibited binding of IL-7 to its receptor and has been utilized in in vivo and in vitro studies of IL-7 in T and B cell development and activation.

Research Use Only
Not intended for human or animal therapeutic or diagnostic use.

Related Links
Use the Spectraviewer to help you plan your experiments. Additional general information about Life Technologies flow cytometry products and support is also available.