|CD45R (B220), Rat IgG2a monoclonal|
|PerCP-Cy®5.5 tandem dye|
Ex/Em and laser configuration:
|488/767 nm, blue laser|
Leukocyte Workshop Status:
The rat anti-mouse CD45R (B220) monoclonal antibody (mAb) reacts with an exon A-specific epitope on CD45 that is expressed on virtually all B cells and is maintained throughout B cell development. The epitope is expressed in a restricted manner by B cells and is also present on lymphokine activated killer (LAK) cells. Although CD45R (B220) is widely used as a pan B cell marker, CD19 may be a more appropriate choice; since CD19 expression appears to be more closely restricted to B cells. Studies show that the rat anti-mouse CD45R (B220) mAb potentiates isotype switching in B cells and inhibits proliferative responses to B cell mitogens.
Research Use Only
Not intended for human or animal therapeutic or diagnostic use.
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