|CD8a, Rat IgG2a monoclonal|
|PerCP-Cy®5.5 tandem dye|
Ex/Em and laser configuration:
|482/695 nm, blue laser|
Leukocyte Workshop Status:
The rat anti-mouse CD8a monoclonal antibody (mAb) reacts with mouse CD8a, which is a cell surface receptor expressed as a homodimer (CD8 alpha/alpha) or as a heterodimer with the CD8 beta chain (CD8 alpha/beta). The homodimer, CD8 alpha/alpha, is expressed in dendritic cells and gamma/delta TCR T cells, which are a subpopulation of intestinal intraepithelial lymphocytes (IELs). While the heterodimer, CD8 alpha/beta, is expressed in a majority of thymocytes and a subpopulation of mature alpha/beta TCR T cells. CD8 binds to MHC class I molecules and plays a role in T-cell development and activation of mature T cells.
Research Use Only
Not intended for human or animal therapeutic or diagnostic use.
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