|CD4, Rat IgG2a monoclonal|
|PerCP-Cy®5.5 tandem dye|
Ex/Em and laser configuration:
|482/695 nm, blue laser|
Leukocyte Workshop Status:
The rat anti-mouse CD4 monoclonal antibody (mAb) reacts with the CD4 antigen expressed on the majority of thymocytes and on the MHC class II restricted subset of mature T cells, including Th cells. As a co-receptor in the TCR complex, CD4 is involved in T-cell activation through its interaction with MHC class II molecules on antigen presenting cells and in signal transduction via the tyrosine-protein kinase, Lck. Mouse CD4 antigen is also reported to be present on multipotential hematopoietic stem cells, bone marrow myeloid precursors, and intrathymic precursors.
Research Use Only
Not intended for human or animal therapeutic or diagnostic use.
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