Antibody Specifications
Description: | CD117 (c-kit), Mouse IgG1 monoclonal |
Label: | PE-Cy®7 tandem dye |
Validated Application: | Flow Cytometry |
Species Reactivity: | Human |
Ex/Em and laser configuration: | 488/767 nm, blue laser |
Clone ID: | 104D2 |
Leukocyte Workshop Status: | NA |
Regulatory Status: | RUO |
CD117 (c-kit)
The mouse anti-human CD117 monoclonal antibody (mAb) reacts with human CD117, a member of the tyrosine kinase receptor family. CD117 is expressed by subsets of hematopoietic progenitor cell and mast cells, where the interaction of CD117 and Steel factor promotes the proliferation and differentiation of hematopoietic progenitor cells and the differentiation of mast cells. CD117 is also expressed by and plays a role in the signaling and activation of melanocytes.
Research Use Only
Not intended for human or animal therapeutic or diagnostic use.
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