The CD117 (c-kit), clone 104D2, PE-Cy®7 conjugate is a mouse monoclonal antibody (mAb) that recognizes human CD117. The R-phycoerythrin (PE)-Cy®7 tandem conjugate permits simultaneous multicolor labeling and detection of multiple targets by utilizing a single excitation source - the 488 nm line of an argon-ion laser.

Antibody Specifications

Description:

CD117 (c-kit), Mouse IgG1 monoclonal

Label:

PE-Cy®7 tandem dye

Validated Application:

Flow Cytometry

Species Reactivity:

Human

Ex/Em and laser configuration:

488/767 nm, blue laser

Clone ID:

104D2

Leukocyte Workshop Status:

NA

Regulatory Status:

RUO

CD117 (c-kit)
The mouse anti-human CD117 monoclonal antibody (mAb) reacts with human CD117, a member of the tyrosine kinase receptor family. CD117 is expressed by subsets of hematopoietic progenitor cell and mast cells, where the interaction of CD117 and Steel factor promotes the proliferation and differentiation of hematopoietic progenitor cells and the differentiation of mast cells. CD117 is also expressed by and plays a role in the signaling and activation of melanocytes.

Research Use Only
Not intended for human or animal therapeutic or diagnostic use.

Related Links
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