|CD144, Rat IgG1 monoclonal|
Ex/Em and laser configuration:
|650/660 nm, red laser|
Leukocyte Workshop Status:
The rat anti-mouse CD144 monoclonal antibody (mAb) reacts with mouse CD144, a member of the type II cadherin family. CD144 is expressed constitutively throughout the entire vasculature, consists of 5 extracellular cadherin domains (ECD), and is anchored to the actin cytoskeleton through its cytoplasmic tail. CD144 mediates homophilic adhesion between neighbouring endothelial cells and is localized within specialized adherens junctions at cell-cell contact points. It is required for numerous endothelial cell functions such as endothelial cell assembly into tubular structures, contact-dependent growth inhibition, migration, and survival.
Research Use Only
Not intended for human or animal therapeutic or diagnostic use.
Use the Spectraviewer to help you plan your experiments. Additional general information about Life Technologies flow cytometry products and support is also available.