|CD278 (ICOS), Armenian Hamster IgG monoclonal|
Ex/Em and laser configuration:
|488/519 nm, blue laser|
Leukocyte Workshop Status:
Hamster anti-mouse/rat CD278 (ICOS) monoclonal antibody (mAb) cross-reacts with both mouse and rat CD278. As a member of the CD28/CTLA-4 family, CD278 is expressed on activated T-cells and has a potent co-stimulatory activity for T-cell activation and proliferation. It is required for the humoral immune response and is thought to play a protective role in inflammatory autoimmune diseases and in the development of Th2 cells. Also CD278 binds to its ligand, B7h/B7RP-1, on activated antigen presenting cells.
Research Use Only
Not intended for human or animal therapeutic or diagnostic use.
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