The CD335 (NKp64), clone 29A1.4, fluorescein (FITC) conjugate is a rat monoclonal antibody (mAb) that reacts with mouse CD335 (NKp64). The commonly used fluorescein (FITC) conjugate provides relatively high absorptivity, excellent fluorescence quantum yield, and good water solubility.


CD335 (NKp64)
The rat anti-mouse CD335 (NKp64) monoclonal antibody (mAb) recognizes mouse CD335, which is a member of the natural cytotoxicity receptor (NCR) family. CD335 is a glycoprotein with 2 Ig-like domains and a short cytoplasmic tail. While other NK markers also stain NKT cells, expression of CD335 is unique only to NK cells, which allows discrimination between NKT cells and NK cells (NKp46+, CD3-), including immature NK cells (DX5- CD3-). Furthermore, the rat anti-mouse CD335 (NKp64) mAb is not strain-specific, with documented staining observed in C57BL/6, SJL, CBA/CA, and BALB/c mice. CD335 also appears to play a role in NK cell-mediated lysis of several tumor and pathogen-infected cell lines.

Research Use Only
Not intended for human or animal therapeutic or diagnostic use.

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