The NK1.1 (Ly-55), clone PK136, APC (allophycocyanin) conjugate is a monoclonal mouse antibody that recognizes the mouse NK1.1 alloantigen. APC is a stable and highly soluble phycobiliprotein that provides maximal absorbance and fluorescence without susceptibility to internal or external fluorescence quenching, thereby affording exceptional quantum yields and molar extinction coefficients. The use of APC in antibody conjugates results in probes with greatly enhanced detectability.




NK1.1 (Ly-55)

NK1.1, a member of the NKR-P1 family of cell surface receptors, is a type-II integral membrane glycoprotein with a C-type lectin domain. It is expressed as a disulfide-linked homodimer on all NK cells, as well as on subsets of thymocytes and peripheral T-lymphocytes in selected strains of mice (e.g., C57BL/6, NZB, and CE). NK1.1 mediates cellular activation and differentiation, and is thought to play a role in generating Th2 cells. This product does not react with NK cells of BALB/c mice.


For Research Use Only. Not intended for human or animal therapeutic or diagnostic use.