|Description:||NK1.1 (Ly-55), Mouse IgG2a monoclonal|
|Validated Application:||Flow Cytometry|
|Ex/Em and laser configuration:||488/519 nm, blue laser|
|Leukocyte Workshop Status:||NA|
NK1.1, a member of the NKR-P1 family of cell surface receptors, is a type II integral membrane glycoprotein with a C-type lectin domain. It is expressed as a disulfide-linked homodimer on all NK cells, as well as on subsets of thymocytes and peripheral T lymphocytes in selected strains of mice (e.g., C57BL/6, NZB, and CE). NK1.1 mediates cellular activation and differentiation, and is thought to play a role in generating Th2 cells. This antibody does not react with NK cells of BALB/c mice.
For Research Use Only. Not intended for human or animal therapeutic or diagnostic use.