|Description:||CD90/Thy-1, Rat IgG2c monoclonal|
|Validated Application:||Flow Cytometry|
|Ex/Em and laser configuration:||496/578 nm, blue laser|
|Leukocyte Workshop Status:||NA|
CD90/Thy-1, a GPI-anchored molecule and one of the smallest members of the immunoglobulin superfamily of cell surface receptors, consists of a single V-set domain. It is expressed on thymocytes, peripheral T lymphocytes, some intraepithelial T lymphocytes, and neurons of all mouse strains. MAb G7 stimulates T-cell proliferation and IL-2 secretion via signaling through the T-cell receptor/CD3 complex. This antibody has also been reported to promote apoptosis of thymocytes and CTL clones, and to mediate the adhesion of thymocytes to the thymic stroma.
For Research Use Only. Not intended for human or animal therapeutic or diagnostic use.