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The AcroMetrix® Inhibition Panel is intended to provide a means of detecting the types of inhibition of nucleic acid amplification methods and serology assays that may be observed as the result of interfering substances commonly found in serum, plasma or whole blood specimens. The AcroMetrix® Inhibition Panel members are designed to mimic the potential interfering substances and clinical conditions, such as haemolysis, icterus, and lipemia. The AcroMetrix® Inhibition Panel also contains representative substances that are frequently used as drugs or anticoagulants (such as heparin) which may cause inhibition of certain assays. For Research Use Only. Not for use in diagnostic procedures. The AcroMetrix® Inhibition Panel members have been carefully formulated to mimic normal human specimens containing naturally occurring interfering substances or interfering substances introduced during routine blood collection processes. The AcroMetrix® Inhibition Panel is designed for use with any assay system used to detect analytes derived or stored in whole blood or blood derivatives. Accordingly, the levels of interfering substances present in each panel member are within the range observed in clinical patient specimens that are tested for many different analytes. Although there is a flexibility in the type of analytes which may be used with the panel, all AcroMetrix® Inhibition Panel members, including EDTA plasma, should be spiked with an equal volume (and concentration) of the desired analyte, so that the interference⁄non-interference claims of the extraction and⁄or assay system are consistently verified.
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