This purified, recombinant, human biotinylated Fab recognizes PRDM9 in human samples.

Recombinant antibody characteristics include:
• Validation in immunoprecipitation
• Superior lot-to-lot consistency
• Extremely high specificity and sensitivity
• Recombinant human biotinylated Fab
• Specific for PRDM9

PRDM9 is a histone methyltransferase that specifically trimethylates Lys-4 of histone H3 during meiotic prophase and is essential for proper meiotic progression. It does not have the ability to mono- and dimethylate the Lys-4. H3 Lys-4 methylation represents a specific tag for epigenetic transcriptional activation and plays a central role in the transcriptional activation of genes during early meiotic prophase.br>
Exceptional Consistency Saves You Time and Money
Recombinant antibodies are produced by transfection of mammalian cells with heavy and light chain antibody cDNAs. This provides you with the highest consistency between lots, eliminating the need to revalidate your assays for each lot.

High Specificity Means More Reliable Data
The recombinant technology employed in manufacture of the antibody assures greatest degree of reliability. Staining of nonspecific proteins is virtually eliminated while very high sensitivity is achieved. Life Technologies has validated this antibody in immunoprecipitation.

High Sensitivity Lets You Detect Low Levels of Target Protein
Recombinant antibodies demonstrate much higher sensitivity than ordinary antibodies. Proteins expressed at low levels can be detected with high specificity allowing you to use less of your precious samples than with ordinary antibodies.

Recombinant Mouse IgG-Use Like Any Other IgG Antibody
As with traditional IgG antibodies, gel electrophoresis of recombinant antibodies produces a 150 kDa band under non-reducing conditions and 50 kDa and 25 kDa bands under reducing conditions.

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