• Validation in immunocytochemistry, western blot, and indirect ELISA
• Isotype: Rabbit IgG
• Concentration: 0.5 mg /ml
• Buffer: Phosphate-buffered saline (PBS) with 0.09% sodium azide
Oligoclonal Antibodies - Exceptional Consistency Helps Save Time and Money
Life Technologies' oligoclonal antibodies are a pool of monoclonal rabbit IgG antibodies targeted against a specific antigen. Oligoclonal antibodies are produced by transfection of mammalian cells with heavy and light chain antibody cDNAs. This provides you with the highest consistency between lots, eliminating the need to revalidate your assays for each lot.
Oligoclonal Antibody Advantages Include:
• Superior lot-to-lot consistency
• Extremely high specificity and sensitivity
• Validation by Life Technologies
Specific for RPS6[pS235/236]
Ribosomal protein 6 (RPS6) is an important component of 40S ribosomal subunit. It belongs to S6E family of ribosomal proteins. RPS6 is a key substrate for kinases phosphorylated by growth fators and mitogens. Phosporylation in RPS6 is well regulated and the different phosphorylation sites are highly conserved (1). RPS6 plays a significant role in cell growth and cell division (2).
Obtain More Reliable Data
The proprietary recombinant technology employed in the production of Life Technologies' oligoclonal antibodies means you are assured of the greatest degree of reliability. Staining of nonspecific proteins is virtually eliminated while very high sensitivity is achieved.
Detect Low Levels of Target Protein
Life Technologies' oligoclonal antibodies demonstrate much higher sensitivity than ordinary antibodies. Proteins expressed in low levels can be detected with high specificity allowing you to use less of your precious samples than with ordinary antibodies.
Recombinant Rabbit IgG - Use Like Any Other IgG Antibody
As with traditional IgG antibodies, gel electrophoresis of rabbit oligoclonal antibodies produces a 150 kDa band under non-reducing conditions and 50 kDa and 25 kDa bands under reducing conditions.
Rapidly Locate the Antibody You Need Using the Antibody Search Tool
- Journal of Biological Chemistry, 286, 8688-8696.
- Genes & Dev. 2005. 19: 2199-2211.