This is a purified rabbit anti-human Insulin oligoclonal antibody (oAb) that can be used in validated applications such as immunofluorescence (IF), immunohistochemistry (IHC), and indirect ELISA.

ABfinity™ antibody characteristics include:

• APPLICATIONS: This Insulin Oligoclonal Antibody, ABfinity™ Recombinant has been validated for use in indirect ELISA and immunocytochemsitry.
• HOST SPECIES AND ISOTYPE: This is a recombinant rabbit oligoclonal IgG against human Insulin.
• CLONE ID OF OLIGOCLONAL (oAb): The oligoclonal antibody clone is 19HCLC.
• REACTIVITY: Along with human Insulin, this oligoclonal antibody is predicted to react with monkey, canine, equine, bat, rat, and rabbit.
• PRODUCT SIZE: 100 µg

Specific for Insulin

Insulin is a hormone secreted by the islet cells of the pancreas. It plays a central role in blood glucose homeostasis. It functions by increasing the cell permeability to monosaccharides, amino acids, and fatty acids. It also accelerates glycolysis, pentose phosphate cycle, and glycogen synthesis in liver. Mature insulin is formed after pro-insulin undergoes cleavage into 3 peptides of which the A and B chains are covalently linked via 2 disulphide bonds. Insulin binds to insulin receptor to stimulate glucose uptake.

Related Links:

Learn more about the superior performance of ABfinity™ recombinant monoclonal antibodies.

See Life Technologies' full line of ABfinity™ recombinant monoclonal antibodies.