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This purified ABfinity™ recombinant rabbit oligoclonal antibody is specific to human β-2-microglobulin. Alternate names for β-2-microglobulin are B2M and B2-microglobulin. ABfinity™ recombinant rabbit oligoclonal antibody is used in western blotting and indirect ELISA applications.
• Applications: Validated applications for rabbit anti-β-2-microglobulin oligoclonal antibody are western blotting and indirect ELISA. • Clone ID of Oligoclonal Antibody (pAb): The oligoclonal antibody clone is 4HCLC. • Host Species and Isotype: The host species and isotype of the antibody is rabbit IgG. • Reactivity: Reacts with human β-2-microglobulin. • Product Size: Rabbit anti-β-2-microglobulin oligoclonal antibody is available in a 100 µg size.
Beta-2-microglobulin is encoded by the b2m gene located on chromosome 15. It is a low molecular weight protein associated with the HLA complex and is an important cell surface structure. The amino acid sequence of β-2-microglobulin is homologous to the constant regions of immunoglobulin heavy and light chains and has a predominantly beta-pleated sheet structure. This protein is ubiquitously expressed in the cytoplasm and is involved in antigen processing and presentation. Beta-2-microglobulin also plays a role in TCR signaling and downstream signaling in naive CD8+ cells.
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