- Applications: Western blot and indirect ELISA
- Host Species and Isotype: Rabbit IgG
- Species Cross-reactivity: Human
Life Technologies' oligoclonal antibodies are a pool of monoclonal rabbit IgG antibodies targeted against a specific antigen. Oligoclonal antibodies are produced by transfection of mammalian cells with heavy and light chain antibody cDNAs. This provides you with the highest consistency between lots, eliminating the need to revalidate your assays for each lot.
Oligoclonal Antibody Advantages Include:
- Superior lot-to-lot consistency
- Extremely high specificity and sensitivity
VPS34 is a class III PI3K (Phosphatidylinositol 3-kinases). PI3K are lipid kinases that regulate several vital cellular processes, including signal transduction, membrane trafficking, cytoskeletal regulation and apoptosis. VPS34 was found to have a role in insulin-stimulated mitogenesis. It is required for internal vesicle formation within multivesicular endosomes. VPS34 and its adapter protein p150 are Rab7 interacting partners, and the hVPS34/p150 complex co-localizes with Rab7 on late endosomes, and hVPS34 activity depends on nucleotide cycling of Rab7.
Obtain More Reliable Data
The proprietary recombinant technology employed in the production of Life Technologies' oligoclonal antibodies means you are assured of the greatest degree of reliability. Staining of nonspecific proteins is virtually eliminated while very high sensitivity is achieved.
Detect Low Levels of Target Protein
Life Technologies' oligoclonal antibodies demonstrate much higher sensitivity than ordinary antibodies. Proteins expressed in low levels can be detected with high specificity allowing you to use less of your precious samples than with ordinary antibodies.
Recombinant Rabbit IgG-Use Like Any Other IgG Antibody
As with traditional IgG antibodies, gel electrophoresis of rabbit oligoclonal antibodies produces a 150 kDa band under non-reducing conditions and 50 kDa and 25 kDa bands under reducing conditions.
For research use only. Not intended for any animal or human therapeutic or diagnostic use.
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