This is a purified rabbit anti-human TIMP4 monoclonal antibody (mAb) that can be used in validated applications such as western blotting (WB), indirect ELISA, immunocytochemistry (ICC), and flow cytometry (FC). ABfinity™ antibody characteristics include:
This TIMP4 Monoclonal Antibody, ABfinity™ Recombinant has been validated for use in western blotting, indirect ELISA, immunocytochemistry, and flow cyotmetry.
• HOST SPECIES AND ISOTYPE:
This is a recombinant rabbit monoclonal IgG against human TIMP4.
• CLONE ID OF MONOCLONAL (mAb):
The monoclonal antibody clone is 13H4L13.
Along with human TIMP4, this monoclonal antibody is predicted to react with monkey, rabbit, bovine, canine, bat, equine, rat, and mouse.
• PRODUCT SIZE:
100 µg Specific for TIMP4
Tissue inhibitor of metalloproteinase 4 (TIMP4) is encoded by the gene TIMP4 located on chromosome 3. It belongs to the family of TIMP genes and is known to inhibit the activity of matrix metalloproteinases. Matrix metalloproteinases (MMP) are a group of proteinases that degrade the components of extracellular matrix. TIMP4 irreversibly binds to MMPs and inactivates them with the help of zinc as a cofactor. The netrin domain of TIMP4 is involved in platelet recruitment and aggregation. Other biological functions include response to cytokine and peptide hormone stimuli and involvement with the ovulation cycle and CNS development. Related Links:Learn more about the superior performance of ABfinity™ recombinant monoclonal antibodies
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