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The purified ABfinity™ Recombinant rabbit anti-Apo E Monoclonal Antibody recognizes Apo E in human samples. Apo E (Apolipoprotein E) plays an important role in the metabolism of lipids in the plasma and is also a constituent of various plasma lipoprotein-lipid particles. This rabbit anti-Apo E Monoclonal Antibody, ABfinity™ Recombinant can be used in applications such as immunocytochemistry, Western blotting and indirect ELISA.
Applications: Validated applications for Apo E monoclonal antibody ABfinity™ Recombinant, rabbit are immunocytochemistry, Western blotting and Indirect ELISA. Host species and isotype: The host species and isotype of the Apo E monoclonal antibody ABfinity™ Recombinant is rabbit IgG. Clone ID of monoclonal antibody (mAb): The Apo E monoclonal antibody ABfinity™ Recombinant, rabbit clone is 16H22L18. Reactivity: Apo E monoclonal antibody ABfinity™ Recombinant, rabbit detects human Apo E. Product size: Apo E Monoclonal Antibody ABfinity™ Recombinant, rabbit is available in a 100 µg pack size.
ABfinity™ antibody characteristics include:
• Validation in immunocytochemistry, Western Blot and indirect ELISA
• Superior lot-to-lot consistency
• Extremely high specificity and sensitivity
• Recombinant rabbit monoclonal antibody
• Specific for Apo E
Apolipoprotein E plays an important role in the metabolism of plasma lipids and is also is a constituent of various plasma lipoprotein—lipid particles. The protein is synthesized in liver, brain, spleen and kidney, though the protein is known to be present in high concentrations in interstitial fluids, where is plays a role in distributing cholesterol to cells which require it. ApoE also plays an important role in the formation of very low density lipoprotein and chylomicrons. The Apo E gene is located on chromosome 19 at position 19q13.2
Exceptional Consistency Saves You Time and Money
ABfinity™ antibodies are produced by transfection of mammalian cells with heavy and light chain antibody cDNAs. This provides you with the highest consistency between lots, eliminating the need to revalidate your assays for each lot.
High Specificity Means More Reliable Data
The proprietary recombinant technology employed in the production of ABfinity™ antibodies means you are assured of the greatest degree of reliability. Staining of nonspecific proteins is virtually eliminated while very high sensitivity is achieved. Life Technologies has validated this antibody in Western blotting.
High Sensitivity Lets You Detect Low Levels of Target Protein
ABfinity™ antibodies demonstrate much higher sensitivity than ordinary antibodies. Proteins expressed in low levels can be detected with high specificity allowing you to use less of your precious samples than with ordinary antibodies.
Recombinant rabbit IgG—Use Like Any Other IgG Antibody
As with traditional IgG antibodies, gel electrophoresis of ABfinity™ antibodies produces a 150 kDa band under non-reducing conditions and 50 kDa and 25 kDa bands under reducing conditions.
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