Specific for GSK3beta
GSK3beta belongs to the subfamily of glycogen synthase kinases that plays a central role in energy metabolism, neuronal cell development, and body pattern formation. GSK3a and GSK3b are two isoforms of sizes 51 kDa and 47 kDa respectively that are not functionally identical. GSK3beta plays a key role in insulin and Wnt signaling, phosphorylating downstream targets by default, and becoming inhibited following extracellular signaling events.
ABfinity™ antibody characteristics include:
- Validation in Western blot and indirect ELISA
- Superior lot-to-lot consistency
- Extremely high specificity and sensitivity
- Recombinant rabbit monoclonal antibody
ABfinity™ antibodies are produced by transfection of mammaliancells with heavy and light chain antibody cDNAs. This provides you withthe highest consistency between lots, eliminating the need torevalidate your assays for each lot.
High Specificity Means More Reliable Data
The proprietary recombinant technology employed in the production ofABfinity™ antibodies means you are assured of the greatest degreeof reliability. Staining of nonspecific proteins is virtuallyeliminated while very high sensitivity is achieved. Life Technologies scientists havevalidated this antibody for Western blotting.
High Sensitivity Lets You Detect Low Levels of Target Protein
ABfinity™ antibodies demonstrate much higher sensitivity thanordinary antibodies. Proteins expressed in low levels can be detectedwith high specificity allowing you to use less of your precious samplesthan with ordinary antibodies.
Recombinant Rabbit IgG—Use Like Any Other IgG Antibody
As with traditional IgG antibodies, gel electrophoresis ofABfinity™ antibodies produces a 150 kDa band under non-reducingconditions and 50 kDa and 25 kDa bands under reducing conditions.
For Research Use Only. Not intended for any animal or human therapeuticor diagnostic use.
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Learn moreabout the superior performance of ABfinity™ recombinantmonoclonal antibodies
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