This purified ABfinity™ recombinant rabbit monoclonal antibody recognizes Syntaxin PEP12 in yeast.

ABfinity™ antibody characteristics include:

• Validation in Western blot
• Superior lot-to-lot consistency
• Extremely high specificity and sensitivity
• Recombinant rabbit monoclonal antibody

Specific for Syntaxin PEP12
Syntaxins belong to a family of SNARE proteins (Ref 1). In yeast, syntaxin is also known as Pep12 protein. In the presence of other cytoplasmic proteins like the N-ethylmaleimide-sensitive factor (NSF) and SNAP, syntaxins can produce important effects on the function and specificity of the vesicular combination process (Ref 2). Function of this Pep12 protein in the yeast is to transport vesicles to the vacuole from the Golgi apparatus.

Exceptional Consistency Saves You Time and Money
ABfinity™ antibodies are produced by transfection of mammalian cells with heavy and light chain antibody cDNAs. This provides you with the highest consistency between lots, eliminating the need to revalidate your assays for each lot.

High Specificity Means More Reliable Data
The proprietary recombinant technology employed in the production of ABfinity™ antibodies means you are assured of the greatest degree of reliability. Staining of nonspecific proteins is virtually eliminated while very high sensitivity is achieved. Invitrogen has validated this antibody in Western blotting.

High Sensitivity Lets You Detect Low Levels of Target Protein
ABfinity™ antibodies demonstrate much higher sensitivity than ordinary antibodies. Proteins expressed in low levels can be detected with high specificity allowing you to use less of your precious samples than with ordinary antibodies.

Recombinant Rabbit IgG--Use Like Any Other IgG Antibody
As with traditional IgG antibodies, gel electrophoresis of ABfinity™ antibodies produces a 150kDa band under non-reducing conditions and 50kDa and 25kDa bands under reducing conditions.

For research use only. Not intended for any human or animal therapeutic or diagnostic use.

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References:

1) Bennett MK, García-Arrarás JE, Elferink LA, Peterson K, Fleming AM, Hazuka CD, Scheller RH. The syntaxin family of vesicular transport receptors. Cell. 1993 10;74(5):863-73. PubMed PMID: 7690687

2) Teng FY, Wang Y, Tang BL. The syntaxins. Genome Biol. 2001;2(11):REVIEWS3012. Epub 2001 Oct 24. Review. PubMed PMID: 11737951.