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This purified ABfinity™ recombinant Rabbit Anti-Rat IL-6 Monoclonal Antibody recognizes IL-6. IL-6 is an interleukin protein (24kDa) encoded by the gene IL6. IL-6 function has been implicated in several diseases such as diabetes, prostate cancer, and rheumatoid arthritis. This anti-rat IL-6 monoclonal antibody can be used in validated applications such as Western Blot.
ABfinity™ IL6 (rat) antibody advantages include:
• Superior lot-to-lot consistency • Extremely high specificity and sensitivity • Recombinant rabbit monoclonal antibody • Validation in western blot
• Applications: The validated application for ABfinity™ recombinant rabbit anti-rat IL-6 monoclonal antibody is western blotting. • Host Species and Isotype: The host species and isotype of the anti-rat IL-6 monoclonal antibody is rabbit IgG. • Reactivity: Detects rat IL-6. • Clone ID of Monoclonal Antibody (mAb): The monoclonal antibody clone is C7H24L3. • Product Size: ABfinity™ Recombinant Rabbit Anti-Rat IL-6 Monoclonal Antibody is available in a 100 µg pack size.
Specific for IL6 IL6 is an interleukin protein (24 kDa) encoded by the Il6 gene (Ref 1). It is secreted by T-cells and macrophages during immune response to tissue damage and trauma, ultimately leading to inflammatory response (Ref 3, 4, 6). IL-6 has been indicated in several diseases such as diabetes (Ref 5), prostate cancer (Ref 8), and rheumatoid arthritis (Ref 7). Physiologically, IL6 synthesis is stimulated by endotoxins, PDGF, TNF, etc.
Exceptional Consistency Helps Save You Time and Money ABfinity™ antibodies are produced by transfection of mammalian cells with heavy and light chain antibody cDNAs. This provides you with high consistency between lots, minimizing the need to revalidate your assays for each lot.
High Specificity Means More Reliable Data The proprietary recombinant technology employed in the production of ABfinity™ antibodies permits an extremely high degree of reliability. Staining of nonspecific proteins is virtually eliminated while very high sensitivity is achieved. Invitrogen has validated this antibody in western blotting (Fig 1).
High Sensitivity Lets You Detect Low Levels of Target Protein ABfinity™ antibodies demonstrate much higher sensitivity than ordinary antibodies. Proteins expressed in low levels can be detected with high specificity allowing you to use less of your precious samples than with ordinary antibodies.
Recombinant Rabbit IgG—Use Like Any Other IgG Antibody As with traditional IgG antibodies, gel electrophoresis of ABfinity™ antibodies produces a 150 kDa band under non-reducing conditions, and 50 kDa and 25 kDa bands under reducing conditions.
For Research Use Only. Not intended for any animal or human therapeutic or diagnostic use.
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