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Rabbit anti-Survivin Monoclonal Antibody ABfinity™ Recombinant is validated to react with human and has an expected reactivity with Bovine, mouse, hamster and rat Survivin. Survivin is encoded by the 332 gene, also known as Baculoviral IAP repeat-containing protein 5, Apoptosis inhibitor 4, IAP4. Survivin has been shown to express in a cell cycle-dependent manner in the G2/M cell cycle and associates with the mitotic apparatus. This Rabbit Anti-Survivin Monoclonal Antibody ABfinity™ Recombinant, is validated for use in Western Blot and Immunofluorescence.
• Applications: Validated applications for Survivin Monoclonal Antibody, Rabbit (clone 9H18L32), ABfinity™ Recombinant are Western Blotting and Immunofluorescence. • Host Species and Isotype: The host species and isotype of the antibody is Rabbit IgG. • Clone ID of Monoclonal Antibody (mAb): The Rabbit Anti-Survivin Monoclonal Antibody ABfinity™ Recombinant clone is 9H18L32. • Reactivity: Rabbit anti-Survivin Monoclonal Antibody ABfinity™ Recombinant reacts with bovine, human, rat, hamster, and mouse Survivin. • Product Size: Rabbit Anti-Survivin Monoclonal Antibody ABfinity™ Recombinant is available in a 100 µg pack size.
Survivin is the smallest member of the Inhibitors of Apoptosis Protein (IAP) gene family and is also known as IAP4. The IAPs are involved in multiple cell functions such as cell signaling, cell division and metabolism. It exhibits differential expression in nearly all human cancers, but not in most normal tissues. Survivin has been shown to express in a cell cycle-dependent manner in the G2/M cell cycle and associates with the mitotic apparatus. The expression of surviving has been shown to be down regulated by expression of wild-type p53.
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