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This purified ABfinity™ recombinant rabbit anti-FAK [pY861] monoclonal antibody is specific to human FAK [pY861] and does not recognize non-phosphorylated FAK protein. Anti-FAK (Focal Adhesion Kinase) [pY861] recognizes the expressed product of the PTK2 gene. FAK plays a central role in cell motility, proliferation, and apoptosis. Applications that this rabbit anti-FAK [pY861] monoclonal antibody can be used in are western blotting and immunofluorescence.
• Applications: Validated applications for rabbit anti-FAK [pY861] monoclonal antibody are western blotting and immunofluorescence. • Host Species and Isotype: The host species and isotype of the FAK [pY861] antibody is rabbit IgG. • Clone ID of Monoclonal Antibody (mAb): The rabbit anti-FAK [pY861] monoclonal antibody clone is 26H16L4. • Reactivity: Reacts to human FAK [pY861]. • Product Size: Rabbit anti-FAK [pY861] monoclonal antibody is available in a 100 µg size.
FAK (Focal adhesion kinase) is a non-receptor protein-tyrosine kinase of signaling pathways and is involved in cell motility, proliferation and apoptosis. FAK activation leads to autophosphorylation Tyr397, which binds to the Src family kinases. Tyrosine 861 on FAK is a major Src phosphorylation site. Recent evidences of FAK activity in human carcinoma cells indicate that FAK is an important target in cancer research.
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