Copy and paste this HTML to embed a link in your website
Paste link in email or IM
Unconjugated polyclonal antibody specific to human and mouse EZH2. This antibody is validated for use in Chromatin Immunoprecipitation (ChIP), and Western blotting. This antibody has been raised against the N-terminus (aa1-343) of the mouse Ezh2 protein. EZH2 is a histone-lysine methyltransferase with activity dependent on its association with other components of the Polycomb Repressive Complexes 2 and 3 (PCR2/3). The PRC2 complex is composed of EED, EZH2, and 3 (PCR2/3). The PRC2 complex is composed of EED, EZH2, SUZ12/JJAZ1, RBBP4 and RBBP. Polycomb group (PcG) family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. EZH2 associates with the embryonic ectoderm development protein (Eed), the VAV1 oncoprotein, and the X-linked nuclear protein. EZH2 may play a role in the hematopoietic and central nervous systems. Over-expression of EZH2 is observed during advanced stages of prostate cancer and breast cancer.
If you continue without changing your settings, we'll assume that you are happy to receive all cookies on Life Technologies websites. However, you can change your cookie settings at any time at the bottom of this page.
To access this page, please close your session and log into the PunchOut session again. You will need to provide an email address on the sign-in page.Please note if you are a punchout to supply center customer, and are viewing this message, your procurement system does not provide the required information to access this tool. Please contact your procurement system administrator for further instructions.