GABAΒ [pS923], R1-Subunit, Phosphospecific Antibody (SKU# 480021) specific to Rat. This antibody is validated for use in WB. GABAB [pS923], R1-Subunit, Phosphospecific Antibody recognizes the expressed product of the GABBR1 gene, also known as gamma-aminobutyric acid (GABA) B receptor, 1, DAAP-188P13.3, FLJ92613, GABAB(1e), GABABR1, GABBR1-3, GPRC3A, dJ271M21.1.1, dJ271M21.1.2, hGB1a, GABA-B receptor, GABAB, subunit 1c, OTTHUMP00000029114, OTTHUMP00000029115, OTTHUMP00000029116, OTTHUMP00000109099, gamma-aminobutyric acid (GABA) B receptor 1, seven transmembrane helix receptor.
Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors: the GABAA and the GABAB subtype of receptors. GABAB receptors are heterodimeric G protein-coupled receptors that mediate slow synaptic inhibition in the central nervous system. Phosphorylation enhances GABAB receptor effector coupling. Phosphorylation of Ser923 is thought to be important in the regulation of GABAB receptor function.