Copy and paste this HTML to embed a link in your website
Paste link in email or IM
Tubulin-βIII, Mouse Monoclonal Antibody (SKU# 480011) is specific to Rat. This antibody is validated for use in Western Blotting and IHC. Tubulin-βIII, Mouse Monoclonal Antibody recognizes the expressed product of the Tubb3 gene, also known as MC1R, TUBB4, beta-4, TUBB3. Tubulin is the major constituent of microtubules, existing as a heterodimer of the a and b subunits. The beta III isoform of tubulin is found almost exclusively in neuronal processes of adult tissues and is therefore an excellent marker for neurons. Neuron specific, posttranslational modifications within the C-terminal domain of beta III tubulin have been shown to be developmentally regulated suggesting that they may serve to modulate the interaction of tubulin with microtubule associated proteins. Additionally, beta III tubulin has been found to be highly expressed in cancer cells such as small cell lung cancer, large cell neuroendocrine carcinoma and adenocarcinomas and is correlated with an increasing histological degree of malignancy.
If you continue without changing your settings, we'll assume that you are happy to receive all cookies on Life Technologies websites. However, you can change your cookie settings at any time at the bottom of this page.
To access this page, please close your session and log into the PunchOut session again. You will need to provide an email address on the sign-in page.Please note if you are a punchout to supply center customer, and are viewing this message, your procurement system does not provide the required information to access this tool. Please contact your procurement system administrator for further instructions.