ApoTrack™ Cytochrome c WB Cocktail (Sku# 459160) provides a means to detect apoptosis while detecting release of cytochrome c, as well as a cytoplasmic and mitochondrial markers with the help of western blot. The permeabilization of mitochondrial outer membrane and the consequent release of cytochrome c and other apoptogenic proteins from the mitochondrial intermembrane space into the cytoplasm is considered hallmark of many apoptotic pathways leading to cell death. Therefore assaying these proteins in mitochondrial and cytoplasmic fractions is of a prime interest of many researchers. This cocktail provides a means to detect cytochrome c, as well as a cytoplasmic and mitochondrial markers.